January 31 – Shirlene Ostrov resigns as chairwoman of the Hawaii Republican Party following a series of tweets posted by vice chairman Edwin Boyette on the party's Twitter account defending people who supported the QAnon conspiracy theory. Additionally, Boyette resigned on January 24 after the tweets were posted the day before.[1]
March 8 – Hawaii reports their first case of the COVID-19 501.V2 variant that originated in South Africa in a person from Oahu with no known travel history.[2]
July 2 – Transair Flight 810 experienced an engine failure shortly after takeoff from Honolulu's Daniel K. Inouye International Airport and attempted to return to the airport but was unable to maintain altitude and ditched into the ocean approximately 2 miles off the coast around 1:30 a.m.[5]
September 8 – The Alohilani Resort in Honolulu will require COVID-19 vaccinations for workers, becoming the first resort hotel in Hawaii to do so. The mandate will take effect on October 15.
