Macías joined the youth academy of Guadalajara in 2011. Six years later, now aged 17, coach Matías Almeyda promoted Macías to the senior squad.[2] On 16 July, he made his professional debut in the 2017 Campeón de Campeones match against Tigres UANL.[3] Six days later, he made his league debut against Toluca in a scoreless draw.[4] On 8 August, Macías scored his first professional goal in a Copa MX match against Juárez.[5] On 28 October, he scored his first brace against Tijuana in a 3–1 home win.[6]
Loan to León
On 9 December 2018, Macías joined León on a one-year loan with an option to buy.[7] He scored his first brace against Querétaro in a 4–0 away victory.[8] He scored eight goals during the regular phase of the 2019 Clausura, making him the top-scoring Mexican player in the tournament at only 19 years old.[9] Macías scored another two goals in the championship stage to take his total goal tally to ten as León progressed to the finals. He missed the finals against Tigres UANL due to receiving a call-up to play with the Mexico national under-20 team at the World Cup in Poland.[10] He was listed on the Best XI of the 2019 Clausura.[11] He finished the 2019 Apertura with eight goals under his name.
Second spell at Guadalajara
On 1 January 2020, Macías returned to Guadalajara after León failed to agree on personal terms with the player.[12]
Prior to the start of the 2020–21 season, Guadalajara participated in the friendly preseason tournament 2020 Copa por México. In the semi-final match against rivals Club América, Macías scored within 19 seconds of the start, marking it as the fastest goal in a Súper Clásico as Guadalajara won 4–3.[13] He finished as the top scorer of the tournament with four goals but did not participate in the final against Cruz Azul due to injury,[14] where the Guadalajara finished as runner-ups.
Loan to Getafe
On 5 July 2021, Macías joined La Liga club Getafe on a season-long loan.[15] He featured in eight matches overall before having his loan terminated early on 31 January 2022.[16]
Third spell at Guadalajara
On 30 June 2022, Macías suffered a major knee injury in training.[17] On 3 December 2023, he made his first competitive appearance in 18 months.[18] On 20 June 2024, Guadalajara released Macías.[19]
Santos Laguna
On 23 June 2024, Macías joined Santos Laguna.[20] After experiencing multiple injury setbacks, Macías was officially ruled out for an indefinite period on September 27.[21]
International career
Youth
On 25 October 2018, Macías was called up by Diego Ramírez to participate in the 2018 CONCACAF U-20 Championship.[22] He scored 10 goals in the tournament, including 4 against Aruba,[23] winning him the Golden Boot of the tournament.[24] As Mexico would finish runner-up in the tournament, he was listed in the Best XI of the tournament.[25] In April 2019, Macías was included in the 21-player squad to represent Mexico at the U-20 World Cup in Poland.[26]
Macías was included in the final roster that participated at the 2018 Toulon Tournament.[27] He would go on to appear in three matches as Mexico finished runners-up.[28]
Macías was included in the final roster that participated in the 2018 Central American and Caribbean Games.[29] He appeared in two group stage matches as Mexico finished last in their group with one point.
On 2 October 2019, under Gerardo Martino, Macías earned his first cap with the senior national team in a friendly match against Trinidad and Tobago, scoring on his debut in the team's 2–0 victory.[32] A couple of days later, he would score in both 2019–20 CONCACAF Nations League fixtures. The first against Bermuda, scoring his first brace with the national team winning 5–1,[33] and the second against Panama, coming on as a substitute to help break a 1–1 deadlock, scoring Mexico's second goal in an eventual 3–1 victory.[34]
