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Kim Ho Min

Kim Ho Min
김호민
Alma materKAIST
AwardsNational R&D Excellence 100 (2018), Asan Award in Medicine for Young Medical Scientists (2018), Young Scientist Award (2018), Agarwal Award (2009)
Scientific career
FieldsLeucine-rich repeat, cryo-EM, structure-based protein engineering, crystallography, structural biology
InstitutionsKAIST, University of California, San Francisco, Institute for Basic Science
Theses
Doctoral advisorsYoo Ook-Joon and Lee Jie-Oh
Korean name
Hangul
김호민
Revised RomanizationKim Homin
McCune–ReischauerKim Homin
WebsiteKAIST profile

Kim Ho Min (Korean김호민) is a biologist and professor in both the Graduate School of Medical Science & Engineering and the Department of Biological Science of KAIST. He was also the chief investigator of the Protein Communication Group in the Center for Biomolecular and Cellular Structure in the Institute for Basic Science in Daejeon from 2018. As part of the World Research Hub Initiative, he was a visiting professor at the Tokyo Institute of Technology.[1]

Education

Kim's formal study of science started at Dongji Middle School (ko) and Kyeongbuk Science High School in 1993. Finishing high school in two years,[2] he went to the Department of Biological Science in KAIST, where he completed his Bachelor of Science, Master of Science, and doctorate. His advisors were Yoo Ook-Joon and Lee Jie-Oh, the former of which paid for Kim's doctoral studies.[3]

Career

He completed three postdoctoral fellows with the first two occurring at KAIST. From 2005, he worked in the Biomedical Research Center under Professor Yoo Ook Joon and then in the Department of Chemistry under Professor Lee Jie-oh. Moving to the US, his final postdoctoral fellowship was in the Department of Biophysics and Biochemistry, University of California, San Francisco under Professor Cheng Yifan. In 2011, he returned to Korea to set up the Disease Molecule Biochemistry Lab in the Graduate School of Medical Science and Engineering (GSMSE) of KAIST.[4] In GSMSE, he started as an assistant professor and later became an associate professor. He has also worked as an adjunct professor in the Department of Biological Science and KI for Biocentury, both in KAIST.[5]

In December 2018, he was selected to the chief investigator of the Protein Communication Group in the new Center for Biomolecular and Cellular Structure in the headquarters of the Institute for Basic Science.[6] His group utilized structural biology techniques and biochemical and cell-biological approaches to research molecular mechanisms of various protein complexes related to immune response and synaptogenesis.[7] The four core facilities in his research group were the Protein Expression Core, High-performance Cryo-EM Core, Protein Crystallization Core, and Computing core for Cryo-EM Image Processing.[8]

Awards and honors

Selected publications

  1. Park, Beom Seok; Song, Dong Hyun; Kim, Ho Min; Choi, Byong-Seok; Lee, Hayyoung; Lee, Jie-Oh (April 2009). "The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex". Nature. 458 (7242): 1191–1195. Bibcode:2009Natur.458.1191P. doi:10.1038/nature07830. PMID 19252480. S2CID 4396446. Retrieved 6 March 2020.
  2. Jin, Mi Sun; Kim, Sung Eun; Heo, Jin Young; Lee, Mi Eun; Kim, Ho Min; Paik, Sang-Gi; Lee, Hayyoung; Lee, Jie-Oh (21 September 2007). "Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide". Cell. 130 (6). Cell Press: 1071–1082. doi:10.1016/j.cell.2007.09.008. PMID 17889651. S2CID 10992433. Retrieved 6 March 2020.
  3. Kim, Ho Min; Park, Beom Seok; Kim, Jung-In; Kim, Sung Eun; Lee, Judong; Oh, Se Cheol; Enkhbayar, Purevjav; Matsushima, Norio; Lee, Hayyoung; Yoo, Ook Joon; Lee, Jie-Oh (7 September 2007). "Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran". Cell. 130 (5). Cell Press: 906–917. doi:10.1016/j.cell.2007.08.002. PMID 17803912. S2CID 18948568. Retrieved 6 March 2020.
  4. Lim, Jae Seok; Kim, Woo-il; Kang, Hoon-Chul; Kim, Se Hoon; Park, Ah Hyung; Park, Eun Kyung; Cho, Young-Wook; Kim, Sangwoo; Kim, Ho Min; Kim, Jeong A.; Kim, Junho; Rhee, Hwanseok; Kang, Seok-Gu; Kim, Heung Dong; Kim, Daesoo; Kim, Dong-Seok; Lee, Jeong Ho (23 March 2015). "Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy". Nature Medicine. 21 (4). Nature Publishing Group: 395–400. doi:10.1038/nm.3824. PMID 25799227. S2CID 9919578. Retrieved 6 March 2020.
  5. Koh, Young Jun; Kim, Hak-Zoo; Hwang, Seong-Ik; Lee, Jeung Eun; Oh, Nuri; Jung, Keehoon; Kim, Minah; Kim, Kyung Eun; Kim, Homin; Lim, Nam-Kyu; Jeon, Choon-Ju; Lee, Gyun Min; Jeon, Byeong Hwa; Nam, Do-Hyun; Sung, Hoon Ki; Nagy, Andras; Yoo, Ook Joon; Koh, Gou Young (17 August 2010). "Double antiangiogenic protein, DAAP, targeting VEGF-A and angiopoietins in tumor angiogenesis, metastasis, and vascular leakage". Cell. 18 (2). Cell Press: 171–184. doi:10.1016/j.ccr.2010.07.001. PMID 20708158. Retrieved 9 March 2020.

References

  1. ^ "Homin Kim: Visiting Associate Professor". International Research Frontiers Initiative. Tokyo Institute of Technology. Retrieved 3 February 2025.
  2. ^ 손석호 (1 January 2020). "[신년특집-우리지역 과학인재 이끈다] 김호민 KAIST 의과학대학원 부교수". 경북일보 (in Korean). Retrieved 6 March 2020. 포항이 고향인 김 교수는 동지중을 졸업하고 1993년 처음 개교한 경북과학고에 1기 입학생으로 진학함으로써, 과학자로의 첫 여정을 시작했다. 2년 만에 과학고를 조기 졸업하고 카이스트에 진학해 학부부터 석사·박사 과정을 거친 후, 미국 샌프란시스코 대학에서 박사 후 연구원으로 4년을 지냈다.
  3. ^ 최준석 (31 December 2021). "질병 유발 단백질 구조 규명한 김호민 교수의 꿈" (in Korean). 주간조선. Retrieved 3 February 2025.
  4. ^ 박성래. "김호민 KAIST 의과학대학원 교수 - "창조적 연구정신으로 단백질 지도 완성한다"". Monthly People (월건인물) (in Korean). Retrieved 6 March 2020.
  5. ^ "Chief Investigator". Center for Biomolecular and Cellular Structure (Protein Communication Group). Institute for Basic Science. Retrieved 6 March 2020.
  6. ^ 이채린 (January 20, 2025). "'무도병' 헌팅턴병 치료하는 샤페론 개발". Donga Science (in Korean). Retrieved 3 February 2025.
  7. ^ "Chief Investigator: CI. Ho Min Kim". Center for Biomolecular and Cellular Structure - Protein Communication Group. Institute for Basic Science. Retrieved 9 March 2020.
  8. ^ "About Group: Introduction". Center for Biomolecular and Cellular Structure. Institute for Basic Science. Retrieved 9 March 2020.
  9. ^ "이재우 교수, 2018 국가연구개발 우수성과 100선 선정리스트에 포함". Department f Chemical and Biomolecular Engineering (in Korean). KAIST. 16 October 2018. Retrieved 9 March 2020.
  10. ^ "2018 국가연구개발 우수성과 100선 선정" (PDF). Ministry of Culture, Sports and Tourism (in Korean). Ministry of Science and ICT. Retrieved 9 March 2020.
  11. ^ 고광보 (10 October 2018). "20조 국가 R&D 과제 중 최우수 연구를 골라라.."유전자치료제·약초보리·방사능탐지…"". 서울경제 (in Korean). Retrieved 9 March 2020.
  12. ^ 김양중 (10 January 2018). "'아산의학상'에 김은준·방영주 교수". 한겨레 (in Korean). Retrieved 9 March 2020.
  13. ^ 박효순 (10 January 2018). "제11회 아산의학상 김은준·방영주 교수 등 수상". 경향신문 (in Korean). Retrieved 9 March 2020.
  14. ^ 임웅재 (10 January 2018). "'11회 아산의학상'에 김은준·방영주 교수". 서울경재 (in Korean). Retrieved 9 March 2020.
  15. ^ "과기정통부·한림원, 2018년 우수과학자 포상 통합시상식 개최". Korean Academy of Science and Technology (in Korean). Retrieved 7 September 2020.
  16. ^ "2011 Agarwal Award 시상식 개최". Graduate School of Medical Science and Engineering (GSMSE) (in Korean). KAIST. 30 August 2018. Retrieved 9 March 2020.
  17. ^ 김태열 (11 January 2018). "제11회 아산의학상 김은준 석좌교수·방영주 교수 수상". 헤럴드경제 (in Korean). Retrieved 9 March 2020.
  18. ^ 김시영 (10 January 2018). "제11회 아산의학상 김은준 석좌교수·방영주 교수 수상". Asia Today (in Korean). Retrieved 9 March 2020.
  19. ^ 김민지 (21 March 2018). "아산재단, 제11회 아산의학상 시상식 개최". 에너지경제 (in Korean). Retrieved 9 March 2020.

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