Strain of virus
LYRa11 is a SARS -like coronavirus (SL-COV) which was identified in 2011 in samples of intermediate horseshoe bats in Baoshan , Yunnan , China. The genome of this virus strain is 29805nt long, and the similarity to the whole genome sequence of SARS-CoV that caused the SARS outbreak is 91%. It was published in 2014.[ 1] SARS-CoV-2 , LYRa11 virus uses ACE2 as a receptor for infecting cells.[ 2]
Phylogenetic
A phylogenetic tree based on whole-genome sequences of SARS-CoV-1 and related coronaviruses is:
See also
References
^ He B; Zhang Y; Xu L; Yang W; Yang F; Feng Y; et al. (2014). "Identification of diverse alphacoronaviruses and genomic characterization of a novel severe acute respiratory syndrome-like coronavirus from bats in China" . J Virol . 88 (12): 7070– 82. doi :10.1128/JVI.00631-14 . PMC 4054348 PMID 24719429 . ^ Wells, H L; Letko, M; Lasso, G; Ssebide, B; Nziza, J; Byarugaba, D K; Navarrete-Macias, I; Liang, E; et al. (2021). "The evolutionary history of ACE2 usage within the coronavirus subgenus Sarbecovirus" . Virus Evolution . 7 (1): veab007. doi :10.1093/ve/veab007 . ISSN 2057-1577 . PMC 7928622 PMID 33754082 . ^ Kim, Yongkwan; Son, Kidong; Kim, Young-Sik; Lee, Sook-Young; Jheong, Weonhwa; Oem, Jae-Ku (2019). "Complete genome analysis of a SARS-like bat coronavirus identified in the Republic of Korea" . Virus Genes . 55 (4): 545– 549. doi :10.1007/s11262-019-01668-w . PMC 7089380 PMID 31076983 . ^ Xu, L; Zhang, F; Yang, W; Jiang, T; Lu, G; He, B; Li, X; Hu, T; Chen, G; Feng, Y; Zhang, Y; Fan, Q; Feng, J; Zhang, H; Tu, C (February 2016). "Detection and characterization of diverse alpha- and betacoronaviruses from bats in China" . Virologica Sinica . 31 (1): 69– 77. doi :10.1007/s12250-016-3727-3 . PMC 7090707 PMID 26847648 . ^ a b Li, W. (2005). "Bats Are Natural Reservoirs of SARS-Like Coronaviruses" . Science . 310 (5748): 676– 679. Bibcode :2005Sci...310..676L . doi :10.1126/science.1118391 . ISSN 0036-8075 . PMID 16195424 . S2CID 2971923 . ^ a b Xing‐Yi Ge; Ben Hu; Zheng‐Li Shi (2015). "BAT CORONAVIRUSES". In Lin-Fa Wang; Christopher Cowled (eds.). Bats and Viruses: A New Frontier of Emerging Infectious Diseases (First ed.). John Wiley & Sons. pp. 127– 155. doi :10.1002/9781118818824.ch5 ^ He, Biao; Zhang, Yuzhen; Xu, Lin; Yang, Weihong; Yang, Fanli; Feng, Yun; et al. (2014). "Identification of diverse alphacoronaviruses and genomic characterization of a novel severe acute respiratory syndrome-like coronavirus from bats in China" . J Virol . 88 (12): 7070– 82. doi :10.1128/JVI.00631-14 . PMC 4054348 PMID 24719429 . ^ a b Lau, Susanna K. P.; Feng, Yun; Chen, Honglin; Luk, Hayes K. H.; Yang, Wei-Hong; Li, Kenneth S. M.; Zhang, Yu-Zhen; Huang, Yi; et al. (2015). "Severe Acute Respiratory Syndrome (SARS) Coronavirus ORF8 Protein Is Acquired from SARS-Related Coronavirus from Greater Horseshoe Bats through Recombination" . Journal of Virology . 89 (20): 10532– 10547. doi :10.1128/JVI.01048-15 . ISSN 0022-538X . PMC 4580176 PMID 26269185 . ^ a b Xing-Yi Ge; Jia-Lu Li; Xing-Lou Yang; et al. (2013). "Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor" . Nature . 503 (7477): 535– 8. Bibcode :2013Natur.503..535G . doi :10.1038/nature12711 . PMC 5389864 PMID 24172901 . ^ Yang, Xing-Lou; Hu, Ben; Wang, Bo; Wang, Mei-Niang; Zhang, Qian; Zhang, Wei; et al. (2016). "Isolation and Characterization of a Novel Bat Coronavirus Closely Related to the Direct Progenitor of Severe Acute Respiratory Syndrome Coronavirus" . Journal of Virology . 90 (6): 3253– 6. doi :10.1128/JVI.02582-15 . PMC 4810638 PMID 26719272 . ^ Ben, Hu; Hua, Guo; Peng, Zhou; Zheng-Li, Shi (2020). "Characteristics of SARS-CoV-2 and COVID-19" . Nature Reviews Microbiology . 19 (3): 141– 154. doi :10.1038/s41579-020-00459-7 . PMC 7537588 PMID 33024307 .
LYRa11 at Wikispecies
