Pol (HIV)Pol (DNA polymerase) refers to a gene in retroviruses, or the protein produced by that gene. Products of pol include: Reverse transcriptaseCommon to all retroviruses, this enzyme transcribes the viral RNA into double-stranded DNA. IntegraseThis enzyme integrates the DNA produced by reverse transcriptase into the host's genome. ProteaseA protease is any enzyme that cuts proteins into segments. HIV's gag and pol genes do not produce their proteins in their final form, but as larger combination proteins; the specific protease used by HIV cleaves these into separate functional units. Protease inhibitor drugs block this step. See alsoExternal links
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