ZNF202

ZNF202
Identifiers
Aliases	ZNF202, ZKSCAN10, ZSCAN42, zinc finger protein 202
External IDs	OMIM: 603430; MGI: 1933401; HomoloGene: 68317; GeneCards: ZNF202; OMA:ZNF202 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	123,741,675 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	40,124,900 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; body of pancreas; ; granulocyte; ; gonad; ; right ovary; ; ventricular zone; ; left ovary; ; left uterine tube; ; body of uterus; ; rectum;
	Top expressed in
	spermatocyte; ; urethra; ; female urethra; ; male urethra; ; tail of embryo; ; genital tubercle; ; ventricular zone; ; trigeminal ganglion; ; yolk sac; ; spermatid;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; nucleic acid binding; DNA-binding transcription factor activity; metal ion binding; DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; intracellular anatomical structure;
Biological process	lipid metabolism; transcription by RNA polymerase II; regulation of transcription, DNA-templated; transcription, DNA-templated; negative regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	7753
	80902
	ENSG00000166261
	ENSMUSG00000025602
	O95125
	n/a
	NM_001301779; NM_001301780; NM_001301819; NM_003455
	NM_030713; NM_001359464
	NP_001288708; NP_001288709; NP_001288748; NP_003446
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger protein 202 is a transcription factor first associated with breast cancer. It is a protein that, in humans, is encoded by the ZNF202 gene.^[5]^[6]

Clinical significance

Variants of this protein have been discovered to be strongly associated with coronary heart disease and atherosclerosis.^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000166261 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025602 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Monaco C, Helmer Citterich M, Caprini E, Vorechovsky I, Russo G, Croce CM, et al. (September 1998). "Molecular cloning and characterization of ZNF202: a new gene at 11q23.3 encoding testis-specific zinc finger proteins". Genomics. 52 (3): 358–362. doi:10.1006/geno.1998.5419. PMID 9790754.
^ "Entrez Gene: ZNF202 zinc finger protein 202".
^ Stene MC, Frikke-Schmidt R, Nordestgaard BG, Steffensen R, Schnohr P, Tybjaerg-Hansen A (September 2006). "Zinc Finger Protein 202: a new candidate gene for ischemic heart disease: The Copenhagen City Heart Study". Atherosclerosis. 188 (1): 43–50. doi:10.1016/j.atherosclerosis.2005.10.014. PMID 16289551.

External links

ZNF202+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000166261 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000025602 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9790754-5] Monaco C, Helmer Citterich M, Caprini E, Vorechovsky I, Russo G, Croce CM, et al. (September 1998). "Molecular cloning and characterization of ZNF202: a new gene at 11q23.3 encoding testis-specific zinc finger proteins". Genomics. 52 (3): 358–362. doi:10.1006/geno.1998.5419. PMID 9790754.

[entrez-6] "Entrez Gene: ZNF202 zinc finger protein 202".

[7] Stene MC, Frikke-Schmidt R, Nordestgaard BG, Steffensen R, Schnohr P, Tybjaerg-Hansen A (September 2006). "Zinc Finger Protein 202: a new candidate gene for ischemic heart disease: The Copenhagen City Heart Study". Atherosclerosis. 188 (1): 43–50. doi:10.1016/j.atherosclerosis.2005.10.014. PMID 16289551.

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ZNF202

Clinical significance

References

Further reading

External links

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