Премия Вольфа по медицине присуждается один раз в год фондом Вольфа в Израиле. Это одна из шести премий Вольфа, учреждённых Фондом, она вручается с 1978; остальные премии включают в себя: сельскохозяйственную, по химии, математике, физике и в области искусств. Является одной из наиболее престижных премий в области медицины.
for their contributions to knowledge of the function and dysfunction of the body cells through their studies on the immunological role of the lymphocytes, the development of specific antibodies and the elucidation of mechanisms governing the control and differentiation of normal and cancer cells.
for her imaginative and important contributions to our understanding of chromosome structure behaviour and function, and for her identification and description of transposable genetic (mobile) elements.
for his concepts underlying genetic engineering; for constructing a biologically functional hybrid plasmid, and for achieving actual expression of a foreign gene implanted in E. coli by the recombinant DNA method.
for his discoveries concerning the bio-synthesis and processing of insulin which have had profound implications for basic biology and clinical medicine.
for the biochemical elucidation of lysosomal storage diseases and the resulting contributions to biology, pathology, prenatal diagnosis and therapeutics.
for his introduction of the xenopus oocyte into molecular biology and his demonstration that the nucleus of a differentiated cell and of the egg differ in expression but not in the content of genetic material.
for his part in the demonstration that the transforming factor in bacteria is due to deoxyribonucleic acid (DNA) and the concomitant discovery that the genetic material is composed of DNA.
for having generated a new field of molecular neurogenetics by his pioneering research on the dissection of the nervous system and behavior by gene mutations.
for his discovery that cancer cells including human tumor cells, carry somatically mutated genes-oncogenes that operate to drive their malignant proliferation.
for his seminal contribution to the design and biological application of novel fluorescent and photolabile molecules to analyze and perturb cell signal transduction.
for pioneering signal transduction therapy and for developing tyrosine kinase inhibitors as effective agents against cancer and a range of other diseases.
for the discovery of protein kinases that phosphorylate tyrosine residues in proteins, critical for the regulation of a wide variety of cellular events, including malignant transformation.
for his discovery of protein domains essential for mediating protein-protein interactions in cellular signaling pathways, and the insights this research has provided into cancer.
for the generation of induced pluripotent stem cells (iPS cells) from skin cells (SY) and demonstration that iPS cells can be used to cure genetic disease in a mammal, thus establishing their therapeutic potential (RJ).
for major contributions to the understanding of the key antigen-specific molecules, the T cell receptor for antigen and antibodies and how these molecules participate in immune recognition and effector function.