Italian bio-engineer
Carlotta Guiducci (born 1977) is an Italian bio-engineer . Her research is invested in bio-molecular analysis based on lab-on-a-chip devices. She is an Associate Professor at EPFL (École polytechnique fédérale de Lausanne) and head of the Laboratory of Life Sciences Electronics located at EPFL 's Lausanne campus.[ 1] [ 2]
Career
Guiducci studied electrical and electronics engineering at University of Bologna and received her Master's degree in 2001. In 2005, she gained a PhD degree in electrical engineering from Department of Electronics, Computer Sciences and Systems (DEIS) at University of Bologna for her work on electronic biosensors and the development of molecular sensors.[ 3] She joined the Nanobiophysics Laboratory at ParisTech as postdoctoral research fellow in 2005.[ 4] In 2007, she returned to University of Bologna as research fellow.[ 5] [ 6]
In 2009, she became a faculty member of the Institute of Bioengineering at the School of Life Sciences at EPFL first as an Assistant Professor, and in 2018, she was promoted as Associate Professor.[ 1] She is the SwissUp Foundation chair, and the founder and head of Laboratory of Life Sciences Electronics.[ 7] [ 8] [ 9]
Research
Guiducci's research centers on biomolecular analysis based on micro-fluidic systems ,[ 10] and on novel personalized medicine approaches.[ 8] [ 11] She is specialized in the integration and interfacing of analytic lab-on-a-chip devices that incorporate full-fledged laboratory equipment on a miniature scale.[ 12] She is developing miniaturized portable devices for DNA-based analytics,[ 11] high-throughput cytometry [ 13] and single-cell analysis .[ 14]
Selected works
Stagni, Claudio; Guiducci, Carlotta; Benini, Luca; Ricco, Bruno; Carrara, Sandro; Samori, Bruno; Paulus, Christian; Schienle, Meinrad; Augustyniak, Marcin; Thewes, Roland (2006). "CMOS DNA Sensor Array with Integrated A/D Conversion Based on Label-Free Capacitance Measurement". IEEE Journal of Solid-State Circuits . 41 (12): 2956– 2964. Bibcode :2006IJSSC..41.2956S . doi :10.1109/JSSC.2006.884867 . S2CID 41863919 .
Cagnin, Stefano; Caraballo, Marcelo; Guiducci, Carlotta; Martini, Paolo; Ross, Marty; Santaana, Mark; Danley, David; West, Todd; Lanfranchi, Gerolamo (2009). "Overview of Electrochemical DNA Biosensors: New Approaches to Detect the Expression of Life" . Sensors . 9 (4): 3122– 3148. Bibcode :2009Senso...9.3122C . doi :10.3390/s90403122 . PMC 3348825 . PMID 22574066 .
Benini, L.; Farella, E.; Guiducci, C. (2006). "Wireless sensor networks: Enabling technology for ambient intelligence". Microelectronics Journal . 37 (12): 1639– 1649. doi :10.1016/j.mejo.2006.04.021 .
Guiducci, C. (2004). "DNA detection by integrable electronics". Biosensors and Bioelectronics . 19 (8): 781– 787. doi :10.1016/S0956-5663(03)00266-5 . PMID 15128096 .
Stagni, Claudio; Guiducci, Carlotta; Benini, Luca; Ricco, Bruno; Carrara, Sandro; Paulus, Christian; Schienle, Meinrad; Thewes, Roland (2007). "A Fully Electronic Label-Free DNA Sensor Chip". IEEE Sensors Journal . 7 (4): 577– 585. Bibcode :2007ISenJ...7..577S . doi :10.1109/JSEN.2007.891990 . S2CID 32564939 .
Cappi, Giulia; Spiga, Fabio M.; Moncada, Yessica; Ferretti, Anna; Beyeler, Michael; Bianchessi, Marco; Decosterd, Laurent; Buclin, Thierry; Guiducci, Carlotta (2015). "Label-Free Detection of Tobramycin in Serum by Transmission-Localized Surface Plasmon Resonance" (PDF) . Analytical Chemistry . 87 (10): 5278– 5285. doi :10.1021/acs.analchem.5b00389 . PMID 25811093 .
Lime, F.; Guiducci, C.; Clerc, R.; Ghibaudo, G.; Leroux, C.; Ernst, T. (2003). "Characterization of effective mobility by split C(V) technique in N-MOSFETs with ultra-thin gate oxides". Solid-State Electronics . 47 (7): 1147– 1153. Bibcode :2003SSEle..47.1147L . doi :10.1016/S0038-1101(03)00049-2 .
References
^ a b "11 professors appointed at ETH Zurich and EPFL | ETH-Board" . www.ethrat.ch . Retrieved 2020-10-01 .
^ "Prof. Carlotta Guiducci" . www.epfl.ch . Retrieved 2020-10-01 .
^ Guiducci, C (2004-03-15). "DNA detection by integrable electronics" . Biosensors and Bioelectronics . 19 (8): 781– 787. doi :10.1016/S0956-5663(03)00266-5 . PMID 15128096 .
^ "NANOBIOPHYSICS LAB/ People" . www.nbp.espci.fr . Retrieved 2020-10-02 .
^ "CARLOTTA GUIDUCCI" . 100 Women and Thousands More . Retrieved 2020-10-02 .
^ Guiducci, Carlotta; Nardini, Christine (2008-04-01). "High parallelism, portability, and broad accessibility: Technologies for genomics" . ACM Journal on Emerging Technologies in Computing Systems . 4 (1): 1– 39. doi :10.1145/1330521.1330524 . ISSN 1550-4832 . S2CID 6216740 .
^ "CLSE" . www.epfl.ch . Retrieved 2020-10-02 .
^ a b "Research at Swiss Up Chair on Engineering" . www.epfl.ch . Retrieved 2020-10-02 .
^ "Rencontre avec Carlotta Guiducci - Radio" . Play RTS (in French). 22 March 2013. Retrieved 2020-10-02 .
^ Thiriet, Pierre-Emmanuel; Pezoldt, Joern; Gambardella, Gabriele; Keim, Kevin; Deplancke, Bart; Guiducci, Carlotta (2020-03-20). "Selective Retrieval of Individual Cells from Microfluidic Arrays Combining Dielectrophoretic Force and Directed Hydrodynamic Flow" . Micromachines . 11 (3): 322. doi :10.3390/mi11030322 . ISSN 2072-666X . PMC 7143322 . PMID 32244902 .
^ a b Tenaglia, Enrico; Ferretti, Anna; Decosterd, Laurent A.; Werner, Dominique; Mercier, Thomas; Widmer, Nicolas; Buclin, Thierry; Guiducci, Carlotta (2018-06-30). "Comparison against current standards of a DNA aptamer for the label-free quantification of tobramycin in human sera employed for therapeutic drug monitoring" . Journal of Pharmaceutical and Biomedical Analysis . 159 : 341– 347. doi :10.1016/j.jpba.2018.06.061 . PMID 30025299 . S2CID 51700744 .
^ Guiducci, Carlotta (2017-07-27). "Integrated electrical sensing for high-throughput bioanalytics" . 2017 IEEE International Conference on IC Design and Technology (ICICDT) . Austin, TX, USA: IEEE. pp. 1– 3. doi :10.1109/ICICDT.2017.7993520 . ISBN 978-1-5090-4502-0 . S2CID 44830895 .
^ Rollo, Enrica; Tenaglia, Enrico; Genolet, Raphaël; Bianchi, Elena; Harari, Alexandre; Coukos, George; Guiducci, Carlotta (2017-08-15). "Label-free identification of activated T lymphocytes through tridimensional microsensors on chip" . Biosensors and Bioelectronics . 94 : 193– 199. doi :10.1016/j.bios.2017.02.047 . PMID 28284079 .
^ Keim, Kevin; Rashed, Mohamed Z.; Kilchenmann, Samuel C.; Delattre, Aurélien; Gonçalves, António F.; Éry, Paul; Guiducci, Carlotta (2019-06-03). "On-chip technology for single-cell arraying, electrorotation-based analysis and selective release" . Electrophoresis . 40 (14): 1830– 1838. doi :10.1002/elps.201900097 . ISSN 0173-0835 . PMC 6771916 . PMID 31111973 .
External links
Information related to Carlotta Guiducci