S12 may refer to:

• Albany Municipal Airport (Oregon), in Linn County, Oregon, United States
• Letov Š-12, a Czechoslovakian prototype fighter aircraft
• Rans S-12 Airaile, an American civil utility aircraft
• SABCA S.XII, a Belgian passenger aircraft
• SIAI S.12, an Italian flying-boat
• Sikorsky S-12, a Russian trainer aircraft
• SPAD S.XII, a French biplane fighter
• Spencer S-12 Air Car, an American amphibious aircraft
• Stemme S12, a German motor glider

• S12 (Rhine-Ruhr S-Bahn), Germany
• S12 (St. Gallen S-Bahn), Switzerland
• S12 (ZVV), Zürich, Switzerland
• Line S12 (Milan suburban railway service), Italy

• Baldwin S-12, a diesel-electric locomotive
• Sri Lanka Railways S12, a diesel multiple unit

• Asari Station (Hokkaido), in Otaru, Hokkaido, Japan
• Bang Wa station, in Bangkok, Thailand
• Iyo-Nagahama Station, in Ōzu, Ehime Prefecture, Japan
• Kikukawa Station, in Sumida, Tokyo, Japan
• Mizuho Kuyakusho Station, in Mizuho-ku, Nagoya, Aichi Prefecture, Japan
• Myōdani Station, in Suma-ku, Kobe, Hyōgo Prefecture, Japan

• Airport Expressway (Beijing), China
• Shanghai–Jiaxing–Huzhou Expressway, China
• S12 highway (Georgia)
• Expressway S12 (Poland)
• County Route S12 (California), United States

• Brazilian submarine Bahia (S-12, 1963), in service 1963–1972
• Brazilian submarine Bahia (S-12, 1973), in service 1972–1993
• HMCS Caribou (S12), an armed yacht of the Royal Canadian Navy
• HMS Olympus (S12), a submarine of the Royal Navy
• USS S-12 (SS-117), a submarine of the United States Navy

• S12 (classification), a disability swimming classification
• 40S ribosomal protein S12
• British NVC community S12, a swamps and tall-herb fens community in the British National Vegetation Classification system
• Lenovo IdeaPad S12, a laptop
• Nissan Silvia (S12), a sports car
• S12: Do not keep the container sealed, a safety phrase
• Saiga-12, a Russian semi-automatic shotgun
• S12, a postcode district in Sheffield, England

Topics referred to by the same term

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